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Foxp3 Instability Helps tTregs Distinguish Self and Non-self

Regulatory T cells (Tregs) are small subsets of CD4 T cells that play a central role in the controlling of immune tolerance. Tregs are either generated in the thymus (tTregs) or the periphery (pTregs), and both express the master transcription factor Foxp3. Stable expression of Foxp3 is important fo...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongmei, Zhou, Xuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769115/
https://www.ncbi.nlm.nih.gov/pubmed/31608056
http://dx.doi.org/10.3389/fimmu.2019.02226