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WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8(+)T Cell Memory

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, micro thrombocytopenia, eczema, and a high incidence of autoimmunity and malignancy. A defect in the T cell compartment is thought to be a major cause of immunodeficiency in patients wit...

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Detalles Bibliográficos
Autores principales: Liu, Qiao, Zhang, Liang, Shu, Zhou, Yu, Tingting, Zhou, Lina, Song, Wenxia, Zhao, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769127/
https://www.ncbi.nlm.nih.gov/pubmed/31608063
http://dx.doi.org/10.3389/fimmu.2019.02262