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WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8(+)T Cell Memory
Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, micro thrombocytopenia, eczema, and a high incidence of autoimmunity and malignancy. A defect in the T cell compartment is thought to be a major cause of immunodeficiency in patients wit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769127/ https://www.ncbi.nlm.nih.gov/pubmed/31608063 http://dx.doi.org/10.3389/fimmu.2019.02262 |