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A consensus set of genetic vulnerabilities to ATR inhibition

The response to DNA replication stress in eukaryotes is under the control of the ataxia–telangiectasia and Rad3-related (ATR) kinase. ATR responds to single-stranded (ss) DNA to stabilize distressed DNA replication forks, modulate DNA replication firing and prevent cells with damaged DNA or incomple...

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Detalles Bibliográficos
Autores principales:	Hustedt, Nicole, Álvarez-Quilón, Alejandro, McEwan, Andrea, Yuan, Jing Yi, Cho, Tiffany, Koob, Lisa, Hart, Traver, Durocher, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769295/ https://www.ncbi.nlm.nih.gov/pubmed/31506018 http://dx.doi.org/10.1098/rsob.190156

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