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Allosteric gate modulation confers K(+) coupling in glutamate transporters
Excitatory amino acid transporters (EAATs) mediate glial and neuronal glutamate uptake to terminate synaptic transmission and to ensure low resting glutamate concentrations. Effective glutamate uptake is achieved by cotransport with 3 Na(+) and 1 H(+), in exchange with 1 K(+). The underlying princip...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769379/ https://www.ncbi.nlm.nih.gov/pubmed/31506973 http://dx.doi.org/10.15252/embj.2019101468 |