In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Although chemotherapy for treating colorectal cancer has had some success, drug resistance and metastasis remain the major causes of death for colorectal cancer patients. MicroRNA-21-5p (hereafter denoted as miR-21) is one of the most abundant miRNAs in human colorectal cancer. A Kaplan–Meier surviv...

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Detalles Bibliográficos
Autores principales: Chen, Jung-Chien, Hsieh, Yao-Yu, Lo, Hsiang-Ling, Li, Albert, Chou, Chia-Jung, Yang, Pei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769444/
https://www.ncbi.nlm.nih.gov/pubmed/31505885
http://dx.doi.org/10.3390/biom9090467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769444/
https://www.ncbi.nlm.nih.gov/pubmed/31505885
http://dx.doi.org/10.3390/biom9090467

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