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Newly Designed Human-Like Collagen to Maximize Sensitive Release of BMP-2 for Remarkable Repairing of Bone Defects

Designing the “ideal” hydrogel/matrix which can load bone morphogenetic protein-2 (BMP-2) in a low dose and with a sustained release is the key for its successful therapeutic application to enhance osteogenesis. The current use of natural collagen sponges as hydrogel/matrix is limited due to the col...

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Detalles Bibliográficos
Autores principales: Chen, Zhuoyue, Zhang, Zhen, Ma, Xiaoxuan, Duan, Zhiguang, Hui, Junfeng, Zhu, Chenhui, Zhang, Donggang, Fan, Daidi, Shang, Lijun, Chen, Fulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769454/
https://www.ncbi.nlm.nih.gov/pubmed/31487971
http://dx.doi.org/10.3390/biom9090450