Elimination of SOX2/OCT4-Associated Prostate Cancer Stem Cells Blocks Tumor Development and Enhances Therapeutic Response

SOX2 and OCT4 are key regulators of embryonic stem cell pluripotency. They are overexpressed in prostate cancers and have been associated with cancer stem cell (CSC) properties. However, reliable tools for detecting and targeting SOX2/OCT4-overexpressing cells are lacking, limiting our understanding...

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Detalles Bibliográficos
Autores principales: Vaddi, Prasanna Kumar, Stamnes, Mark A., Cao, Huojun, Chen, Songhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769476/
https://www.ncbi.nlm.nih.gov/pubmed/31500347
http://dx.doi.org/10.3390/cancers11091331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769476/
https://www.ncbi.nlm.nih.gov/pubmed/31500347
http://dx.doi.org/10.3390/cancers11091331

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