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The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets. As a better understanding of MMP biology and inhibitor pharmacokinetic properties emerged, it bec...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769477/ https://www.ncbi.nlm.nih.gov/pubmed/31461880 http://dx.doi.org/10.3390/cells8090984 |