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FAK-Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer

Background: Cancers with copy-gain drug-target genes are excellent candidates for targeted therapy. In order to search for new predictive marker genes, we investigated the correlation between sensitivity to targeted drugs and the copy gain of candidate target genes in NCI-60 cells. Methods: For eigh...

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Detalles Bibliográficos
Autores principales: Kim, Young-Ho, Kim, Hyun-Kyoung, Kim, Hee Yeon, Gawk, HyeRan, Bae, Seung-Hyun, Sim, Hye Won, Kang, Eun-Kyung, Seoh, Ju-Young, Jang, Hyonchol, Hong, Kyeong-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769494/
https://www.ncbi.nlm.nih.gov/pubmed/31480645
http://dx.doi.org/10.3390/cancers11091288