Cargando…
FAK-Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer
Background: Cancers with copy-gain drug-target genes are excellent candidates for targeted therapy. In order to search for new predictive marker genes, we investigated the correlation between sensitivity to targeted drugs and the copy gain of candidate target genes in NCI-60 cells. Methods: For eigh...
Autores principales: | Kim, Young-Ho, Kim, Hyun-Kyoung, Kim, Hee Yeon, Gawk, HyeRan, Bae, Seung-Hyun, Sim, Hye Won, Kang, Eun-Kyung, Seoh, Ju-Young, Jang, Hyonchol, Hong, Kyeong-Man |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769494/ https://www.ncbi.nlm.nih.gov/pubmed/31480645 http://dx.doi.org/10.3390/cancers11091288 |
Ejemplares similares
-
Backtracking on FAK
por: Leslie, Mitch
Publicado: (2008) -
FAK monitoring
por: Metzmacher, K D
Publicado: (1974) -
An Aqueous Extract of Herbal Medicine ALWPs Enhances Cognitive Performance and Inhibits LPS-Induced Neuroinflammation via FAK/NF-κB Signaling Pathways
por: Lee, Ju-Young, et al.
Publicado: (2018) -
LRRK2 Inhibits FAK Activity by Promoting FERM-mediated Autoinhibition of FAK and Recruiting the Tyrosine Phosphatase, SHP-2
por: Choi, Insup, et al.
Publicado: (2016) -
Urokinase-derived peptide UP-7 suppresses tumor angiogenesis and metastasis through inhibition of FAK activation
por: Kim, Hyun-Kyung, et al.
Publicado: (2018)