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Lithocholic Acid, a Metabolite of the Microbiome, Increases Oxidative Stress in Breast Cancer

In breast cancer patients, the diversity of the microbiome decreases, coinciding with decreased production of cytostatic bacterial metabolites like lithocholic acid (LCA). We hypothesized that LCA can modulate oxidative stress to exert cytostatic effects in breast cancer cells. Treatment of breast c...

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Detalles Bibliográficos
Autores principales: Kovács, Patrik, Csonka, Tamás, Kovács, Tünde, Sári, Zsanett, Ujlaki, Gyula, Sipos, Adrien, Karányi, Zsolt, Szeőcs, Dóra, Hegedűs, Csaba, Uray, Karen, Jankó, Laura, Kiss, Máté, Kiss, Borbála, Laoui, Damya, Virág, László, Méhes, Gábor, Bai, Péter, Mikó, Edit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769524/
https://www.ncbi.nlm.nih.gov/pubmed/31461945
http://dx.doi.org/10.3390/cancers11091255