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Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion

Hypoxia is a common characteristic of advanced solid tumors and a potent driver of tumor invasion and metastasis. Recent evidence suggests the involvement of autotaxin (ATX) and lysophosphatidic acid receptors (LPARs) in cancer cell invasion promoted by the hypoxic tumor microenvironment; however, t...

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Detalles Bibliográficos
Autores principales: Harper, Kelly, Brochu-Gaudreau, Karine, Saucier, Caroline, M. Dubois, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769543/
https://www.ncbi.nlm.nih.gov/pubmed/31546971
http://dx.doi.org/10.3390/cancers11091403