Dietary Polyacetylenic Oxylipins Falcarinol and Falcarindiol Prevent Inflammation and Colorectal Neoplastic Transformation: A Mechanistic and Dose-Response Study in A Rat Model

Falcarinol (FaOH) and falcarindiol (FaDOH) are cytotoxic and anti-inflammatory polyacetylenic oxylipins, which are commonly found in the carrot family (Apiaceae). FaOH and FaDOH have previously demonstrated a chemopreventive effect on precursor lesions of colorectal cancer (CRC) in azoxymethane (AOM...

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Detalles Bibliográficos
Autores principales: Kobaek-Larsen, Morten, Baatrup, Gunnar, K. Notabi, Martine, El-Houri, Rime Bahij, Pipó-Ollé, Emma, Christensen Arnspang, Eva, Christensen, Lars Porskjær
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769548/
https://www.ncbi.nlm.nih.gov/pubmed/31540047
http://dx.doi.org/10.3390/nu11092223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769548/
https://www.ncbi.nlm.nih.gov/pubmed/31540047
http://dx.doi.org/10.3390/nu11092223

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