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HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways

Heat shock factor 1 (HSF1) is an essential transcription factor in cellular adaptation to various stresses such as heat, proteotoxic stress, metabolic stress, reactive oxygen species, and heavy metals. HSF1 promotes cancer development and progression, and increased HSF1 levels are frequently observe...

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Detalles Bibliográficos
Autores principales: Kang, Hyeji, Oh, Taerim, Bahk, Young Yil, Kim, Geon-Hee, Kan, Sang-Yeon, Shin, Dong Hoon, Kim, Ji Hyung, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769575/
https://www.ncbi.nlm.nih.gov/pubmed/31540279
http://dx.doi.org/10.3390/cancers11091363