splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants

Familial Parkinson’s disease (PD) is associated with duplication or mutations of α-synuclein gene, whose product is a presynaptic cytosolic protein also found in mitochondria and in mitochondrial-associated ER membranes. We have originally shown the role of α-syn as a modulator of the ER-mitochondri...

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Detalles Bibliográficos
Autores principales: Calì, Tito, Ottolini, Denis, Vicario, Mattia, Catoni, Cristina, Vallese, Francesca, Cieri, Domenico, Barazzuol, Lucia, Brini, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769576/
https://www.ncbi.nlm.nih.gov/pubmed/31547305
http://dx.doi.org/10.3390/cells8091072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769576/
https://www.ncbi.nlm.nih.gov/pubmed/31547305
http://dx.doi.org/10.3390/cells8091072

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