Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

Sesquiterpenes, the main components of plant essential oils, are bioactive compounds with numerous health-beneficial activities. Sesquiterpenes can interact with concomitantly administered drugs due to the modulation of drug-metabolizing enzymes (DMEs). The aim of this study was to evaluate the modu...

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Detalles Bibliográficos
Autores principales: Šadibolová, Michaela, Zárybnický, Tomáš, Smutný, Tomáš, Pávek, Petr, Šubrt, Zdeněk, Matoušková, Petra, Skálová, Lenka, Boušová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769599/
https://www.ncbi.nlm.nih.gov/pubmed/31540101
http://dx.doi.org/10.3390/ijms20184562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769599/
https://www.ncbi.nlm.nih.gov/pubmed/31540101
http://dx.doi.org/10.3390/ijms20184562

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