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Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver

Sesquiterpenes, the main components of plant essential oils, are bioactive compounds with numerous health-beneficial activities. Sesquiterpenes can interact with concomitantly administered drugs due to the modulation of drug-metabolizing enzymes (DMEs). The aim of this study was to evaluate the modu...

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Detalles Bibliográficos
Autores principales:	Šadibolová, Michaela, Zárybnický, Tomáš, Smutný, Tomáš, Pávek, Petr, Šubrt, Zdeněk, Matoušková, Petra, Skálová, Lenka, Boušová, Iva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769599/ https://www.ncbi.nlm.nih.gov/pubmed/31540101 http://dx.doi.org/10.3390/ijms20184562

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