Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing

Upon tumor antigen recognition, cytotoxic T lymphocytes (CTLs) and target cells form specialized supramolecular structures, called cytotoxic immunological synapses, which are required for polarized delivery of cytotoxic granules. In previous reports, we described the accumulation of connexin 43 (Cx4...

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Detalles Bibliográficos
Autores principales: Hofmann, Francisca, Navarrete, Mariela, Álvarez, Javiera, Guerrero, Israel, Gleisner, María Alejandra, Tittarelli, Andrés, Salazar-Onfray, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769613/
https://www.ncbi.nlm.nih.gov/pubmed/31547237
http://dx.doi.org/10.3390/ijms20184509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769613/
https://www.ncbi.nlm.nih.gov/pubmed/31547237
http://dx.doi.org/10.3390/ijms20184509

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