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Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening

Fungal diseases are a serious health burden worldwide with drug resistance compromising efficacy of the limited arsenal of antifungals available. New drugs with novel mechanisms of action are desperately needed to overcome current challenges. The screening of the Aspergillus fumigatus genome identif...

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Detalles Bibliográficos
Autores principales: Thornton, Benjamin P., Johns, Anna, Al-Shidhani, Reem, Álvarez-Carretero, Sandra, Storer, Isabelle S. R., Bromley, Michael J., Tabernero, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769645/
https://www.ncbi.nlm.nih.gov/pubmed/31546755
http://dx.doi.org/10.3390/ijms20184636