Glycolipids Recognized by A2B5 Antibody Promote Proliferation, Migration, and Clonogenicity in Glioblastoma Cells

A2B5+ cells isolated from human glioblastomas exhibit cancer stem cell properties. The A2B5 epitope belongs to the sialoganglioside family and is synthetized by the ST8 alpha-N-acetyl-neuraminidase α-2,8-sialyltransferase 3 (ST8SIA3) enzyme. Glycolipids represent attractive targets for solid tumors;...

Descripción completa

Detalles Bibliográficos
Autores principales: Baeza-Kallee, Nathalie, Bergès, Raphaël, Soubéran, Aurélie, Colin, Carole, Denicolaï, Emilie, Appay, Romain, Tchoghandjian, Aurélie, Figarella-Branger, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769647/
https://www.ncbi.nlm.nih.gov/pubmed/31466399
http://dx.doi.org/10.3390/cancers11091267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769647/
https://www.ncbi.nlm.nih.gov/pubmed/31466399
http://dx.doi.org/10.3390/cancers11091267

Ejemplares similares