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Modulating Shrimp Tropomyosin-Mediated Allergy: Hypoallergen DNA Vaccines Induce Regulatory T Cells to Reduce Hypersensitivity in Mouse Model

Shellfish allergy is one of the most common food allergies, with tropomyosin as the major cross-reactive allergen. However, no allergen-specific immunotherapy is clinically available. Recently, we designed two shrimp hypoallergens MEM49 and MED171. This study aimed to examine and compare the efficac...

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Detalles Bibliográficos
Autores principales: Wai, Christine Y.Y., Leung, Nicki Y.H., Leung, Patrick S.C., Chu, Ka Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769673/
https://www.ncbi.nlm.nih.gov/pubmed/31546958
http://dx.doi.org/10.3390/ijms20184656