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A Yersinia ruckeri TIR Domain-Containing Protein (STIR-2) Mediates Immune Evasion by Targeting the MyD88 Adaptor

TIR domain-containing proteins are essential for bacterial pathogens to subvert host defenses. This study describes a fish pathogen, Yersinia ruckeri SC09 strain, with a novel TIR domain-containing protein (STIR-2) that affects Toll-like receptor (TLR) function. STIR-2 was identified in Y. ruckeri b...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Wei, Wen-Yan, Wang, Kai-Yu, Wang, Er-Long, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769684/
https://www.ncbi.nlm.nih.gov/pubmed/31500298
http://dx.doi.org/10.3390/ijms20184409