3D Quantitative and Ultrastructural Analysis of Mitochondria in a Model of Doxorubicin Sensitive and Resistant Human Colon Carcinoma Cells

Drug resistance remains a major obstacle in cancer treatment. Because mitochondria mediate metabolic reprogramming in cancer drug resistance, we focused on these organelles in doxorubicin sensitive and resistant colon carcinoma cells. We employed soft X-ray cryo nano-tomography to map three-dimensio...

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Detalles Bibliográficos
Autores principales: Moscheni, Claudia, Malucelli, Emil, Castiglioni, Sara, Procopio, Alessandra, De Palma, Clara, Sorrentino, Andrea, Sartori, Patrizia, Locatelli, Laura, Pereiro, Eva, Maier, Jeanette A., Iotti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769783/
https://www.ncbi.nlm.nih.gov/pubmed/31461915
http://dx.doi.org/10.3390/cancers11091254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769783/
https://www.ncbi.nlm.nih.gov/pubmed/31461915
http://dx.doi.org/10.3390/cancers11091254

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