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3D Quantitative and Ultrastructural Analysis of Mitochondria in a Model of Doxorubicin Sensitive and Resistant Human Colon Carcinoma Cells
Drug resistance remains a major obstacle in cancer treatment. Because mitochondria mediate metabolic reprogramming in cancer drug resistance, we focused on these organelles in doxorubicin sensitive and resistant colon carcinoma cells. We employed soft X-ray cryo nano-tomography to map three-dimensio...
Autores principales: | Moscheni, Claudia, Malucelli, Emil, Castiglioni, Sara, Procopio, Alessandra, De Palma, Clara, Sorrentino, Andrea, Sartori, Patrizia, Locatelli, Laura, Pereiro, Eva, Maier, Jeanette A., Iotti, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769783/ https://www.ncbi.nlm.nih.gov/pubmed/31461915 http://dx.doi.org/10.3390/cancers11091254 |
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