Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism

The most commonly mutated gene in all human cancers is the tumor suppressor gene TP53; however, in addition to the loss of tumor suppressor functions, mutations in TP53 can also promote cancer progression by altering cellular iron acquisition and metabolism. The primary objective of this work was to...

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Detalles Bibliográficos
Autores principales: Clarke, Stephen L., Thompson, Laurie R., Dandekar, Eshan, Srinivasan, Aishwarya, Montgomery, McKale R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769808/
https://www.ncbi.nlm.nih.gov/pubmed/31500291
http://dx.doi.org/10.3390/nu11092144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769808/
https://www.ncbi.nlm.nih.gov/pubmed/31500291
http://dx.doi.org/10.3390/nu11092144

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