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Distinct TP53 Mutation Subtypes Differentially Influence Cellular Iron Metabolism
The most commonly mutated gene in all human cancers is the tumor suppressor gene TP53; however, in addition to the loss of tumor suppressor functions, mutations in TP53 can also promote cancer progression by altering cellular iron acquisition and metabolism. The primary objective of this work was to...
Autores principales: | Clarke, Stephen L., Thompson, Laurie R., Dandekar, Eshan, Srinivasan, Aishwarya, Montgomery, McKale R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769808/ https://www.ncbi.nlm.nih.gov/pubmed/31500291 http://dx.doi.org/10.3390/nu11092144 |
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