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CD8+ and Regulatory T cells Differentiate Tumor Immune Phenotypes and Predict Survival in Locally Advanced Head and Neck Cancer

Background: The tumor immune status “inflamed”, “immune excluded”, and “desert” might serve as a predictive parameter. We studied these three cancer immune phenotypes while using a simple immunohistochemical algorithm. Methods: Pre-treatment tissue samples of 280 patients with locally advanced HNSCC...

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Detalles Bibliográficos
Autores principales: Echarti, Alessia, Hecht, Markus, Büttner-Herold, Maike, Haderlein, Marlen, Hartmann, Arndt, Fietkau, Rainer, Distel, Luitpold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769847/
https://www.ncbi.nlm.nih.gov/pubmed/31546872
http://dx.doi.org/10.3390/cancers11091398