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Mutant Huntingtin Affects Diabetes and Alzheimer’s Markers in Human and Cell Models of Huntington’s Disease

A higher incidence of diabetes was observed among family members of individuals affected by Huntington’s Disease with no follow-up studies investigating the genetic nature of the observation. Using a genome-wide association study (GWAS), RNA sequencing (RNA-Seq) analysis and western blotting of Ratt...

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Detalles Bibliográficos
Autores principales: Chaves, Gepoliano, Stanley, John, Pourmand, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769852/
https://www.ncbi.nlm.nih.gov/pubmed/31450785
http://dx.doi.org/10.3390/cells8090962