Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization

The oncogenic gammaherpesvirus Epstein–Barr virus (EBV) immortalizes in vitro B lymphocytes into lymphoblastoid cell lines (LCLs), a model that gives the opportunity to explore the molecular mechanisms driving viral tumorigenesis. In this study, we addressed the potential of quercetin, a widely dist...

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Detalles Bibliográficos
Autores principales: Granato, Marisa, Gilardini Montani, Maria Saveria, Zompetta, Claudia, Santarelli, Roberta, Gonnella, Roberta, Romeo, Maria Anele, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769872/
https://www.ncbi.nlm.nih.gov/pubmed/31547402
http://dx.doi.org/10.3390/biom9090482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769872/
https://www.ncbi.nlm.nih.gov/pubmed/31547402
http://dx.doi.org/10.3390/biom9090482

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