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Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization
The oncogenic gammaherpesvirus Epstein–Barr virus (EBV) immortalizes in vitro B lymphocytes into lymphoblastoid cell lines (LCLs), a model that gives the opportunity to explore the molecular mechanisms driving viral tumorigenesis. In this study, we addressed the potential of quercetin, a widely dist...
Autores principales: | Granato, Marisa, Gilardini Montani, Maria Saveria, Zompetta, Claudia, Santarelli, Roberta, Gonnella, Roberta, Romeo, Maria Anele, D’Orazi, Gabriella, Faggioni, Alberto, Cirone, Mara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769872/ https://www.ncbi.nlm.nih.gov/pubmed/31547402 http://dx.doi.org/10.3390/biom9090482 |
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