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A Multi-Center Study of BRCA1 and BRCA2 Germline Mutations in Mexican-Mestizo Breast Cancer Families Reveals Mutations Unreported in Latin American Population

The presence of germline and somatic deleterious mutations in the BRCA1 and BRCA2 genes has important clinical consequences for breast cancer (BC) patients. Analysis of the mutational status in BRCA genes is not yet common in public Latin American institutions; thus, our objective was to implement h...

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Detalles Bibliográficos
Autores principales: Millan Catalan, Oliver, Campos-Parra, Alma D., Vázquez-Romo, Rafael, Cantú de León, David, Jacobo-Herrera, Nadia, Morales-González, Fermín, López-Camarillo, César, Rodríguez-Dorantes, Mauricio, López-Urrutia, Eduardo, Pérez-Plasencia, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769960/
https://www.ncbi.nlm.nih.gov/pubmed/31454914
http://dx.doi.org/10.3390/cancers11091246