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Regulatory Effects and Interactions of the Wnt and OPG-RANKL-RANK Signaling at the Bone-Cartilage Interface in Osteoarthritis

Cartilage and the bordering subchondral bone form a functionally active regulatory interface with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK signaling systems, as key mediators, interact in subchondral bone remodeling. Osteoarthritic osteoblasts polarize into two dis...

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Detalles Bibliográficos
Autores principales: Kovács, Béla, Vajda, Enikő, Nagy, Előd Ernő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769977/
https://www.ncbi.nlm.nih.gov/pubmed/31546898
http://dx.doi.org/10.3390/ijms20184653