Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

FOXO transcription factors regulate cellular homeostasis, longevity and response to stress. FOXO1 (also known as FKHR) is a key regulator of hepatic glucose production and lipid metabolism, and its specific inhibition may have beneficial effects on diabetic hyperglycemia by reducing hepatic glucose...

Descripción completa

Detalles Bibliográficos
Autores principales: Psenakova, Katarina, Kohoutova, Klara, Obsilova, Veronika, Ausserlechner, Michael J., Veverka, Vaclav, Obsil, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770010/
https://www.ncbi.nlm.nih.gov/pubmed/31450545
http://dx.doi.org/10.3390/cells8090966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770010/
https://www.ncbi.nlm.nih.gov/pubmed/31450545
http://dx.doi.org/10.3390/cells8090966

Ejemplares similares