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Human Ovarian Cancer Tissue Exhibits Increase of Mitochondrial Biogenesis and Cristae Remodeling

Ovarian cancer (OC) is the most lethal gynecologic cancer characterized by an elevated apoptosis resistance that, potentially, leads to chemo-resistance in the recurrent disease. Mitochondrial oxidative phosphorylation was found altered in OC, and mitochondria were proposed as a target for therapy....

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Detalles Bibliográficos
Autores principales: Signorile, Anna, De Rasmo, Domenico, Cormio, Antonella, Musicco, Clara, Rossi, Roberta, Fortarezza, Francesco, Palese, Luigi Leonardo, Loizzi, Vera, Resta, Leonardo, Scillitani, Giovanni, Cicinelli, Ettore, Simonetti, Francesca, Ferretta, Anna, Russo, Silvia, Tufaro, Antonio, Cormio, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770021/
https://www.ncbi.nlm.nih.gov/pubmed/31547300
http://dx.doi.org/10.3390/cancers11091350