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Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure

SIMPLE SUMMARY: In this study, the phenomenon of ‘autophagy’ was demonstrated in the hippocampus following cold exposure. Persistent neuronal stimulation of the hippocampus after corticosterone (CORT) treatment induced mitochondrial damage and autophagy by activating the AMPK/mTOR signaling pathway,...

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Detalles Bibliográficos
Autores principales: Xu, Bin, Lang, Limin, Li, Shize, Yuan, Jianbin, Wang, Jianfa, Yang, Huanmin, Lian, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770033/
https://www.ncbi.nlm.nih.gov/pubmed/31540011
http://dx.doi.org/10.3390/ani9090682