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MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues

Sarcomas are deadly malignant tumors of mesenchymal origin occurring at all ages. The expression and function of the membrane-type matrix metalloproteinase MMP14 is closely related to the mesenchymal cell phenotype, and it is highly expressed in most sarcomas. MMP14 regulates the activity of multipl...

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Detalles Bibliográficos
Autores principales: Gonzalez-Molina, Jordi, Gramolelli, Silvia, Liao, Zehuan, Carlson, Joseph W., Ojala, Päivi M., Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770050/
https://www.ncbi.nlm.nih.gov/pubmed/31466240
http://dx.doi.org/10.3390/cells8090991