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Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition

Natural hematopoietic stem cells (HSC) are susceptible and tend to lose stemness, differentiate, or die on culture condition in vitro, which adds technical challenge for maintaining bona fide HSC-like cells, if ever generated, in protocol screening from pluripotent stem cells. It remains largely unk...

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Detalles Bibliográficos
Autores principales: Dong, Yong, Xia, Chengxiang, Weng, Qitong, Wang, Tongjie, Hu, Fangxiao, Wang, Kaitao, Liu, Xiaofei, Geng, Yang, Liu, Lijuan, Wu, Hongling, Du, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770072/
https://www.ncbi.nlm.nih.gov/pubmed/31443434
http://dx.doi.org/10.3390/cells8090951