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Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies

Flavonoids are known to play a role in hypoglycemia by inhibiting α-glucosidase. However, their interaction mechanism with α-glucosidase still needs to be elaborated. In this study, the α-glucosidase inhibitory activities of 15 flavonoids were investigated. Their molecular volume had a negative effe...

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Detalles Bibliográficos
Autores principales: He, Chengyun, Liu, Xiaoling, Jiang, Zhaojing, Geng, Sheng, Ma, Hanjun, Liu, Benguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770089/
https://www.ncbi.nlm.nih.gov/pubmed/31438605
http://dx.doi.org/10.3390/foods8090355