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The Relationship between Embryonic Development and the Efficiency of Target Mutations in Porcine Endogenous Retroviruses (PERVs) Pol Genes in Porcine Embryos

SIMPLE SUMMARY: Pigs with porcine endogenous retrovirus (PERV) inactivation are preferable donor sources for xenotransplantation because the PERV may act as an infectious pathogen for humans who receive pig organ xenotransplantation. However, inactivation of the PERV pol gene in porcine cells report...

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Detalles Bibliográficos
Autores principales: Hirata, Maki, Wittayarat, Manita, Hirano, Takayuki, Nguyen, Nhien Thi, Le, Quynh Anh, Namula, Zhao, Fahrudin, Mokhamad, Tanihara, Fuminori, Otoi, Takeshige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770129/
https://www.ncbi.nlm.nih.gov/pubmed/31443357
http://dx.doi.org/10.3390/ani9090593