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Anthracyclines Suppress Both NADPH Oxidase- Dependent and -Independent NETosis in Human Neutrophils

Neutrophil extracellular traps (NETs) are cytotoxic DNA-protein complexes that play positive and negative roles in combating infection, inflammation, organ damage, autoimmunity, sepsis and cancer. However, NETosis regulatory effects of most of the clinically used drugs are not clearly established. S...

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Detalles Bibliográficos
Autores principales: Khan, Meraj A., D’Ovidio, Adam, Tran, Harvard, Palaniyar, Nades
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770146/
https://www.ncbi.nlm.nih.gov/pubmed/31500300
http://dx.doi.org/10.3390/cancers11091328