A Multi-Biochemical and In Silico Study on Anti-Enzymatic Actions of Pyroglutamic Acid against PDE-5, ACE, and Urease Using Various Analytical Techniques: Unexplored Pharmacological Properties and Cytotoxicity Evaluation

In the current study, pyroglutamic acid (pGlu), a natural amino acid derivative, has efficiently inhibited the catalytic activities of three important enzymes, namely: Human recombinant phosphodiesterase-5A1 (PDE5A1), human angiotensin-converting enzyme (ACE), and urease. These enzymes were reported...

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Detalles Bibliográficos
Autores principales: Šudomová, Miroslava, Hassan, Sherif T. S., Khan, Haroon, Rasekhian, Mahsa, Nabavi, Seyed Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770154/
https://www.ncbi.nlm.nih.gov/pubmed/31438631
http://dx.doi.org/10.3390/biom9090392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770154/
https://www.ncbi.nlm.nih.gov/pubmed/31438631
http://dx.doi.org/10.3390/biom9090392

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