Overcoming Immunological Resistance Enhances the Efficacy of a Novel Anti-tMUC1-CAR T Cell Treatment against Pancreatic Ductal Adenocarcinoma

Chimeric antigen receptor (CAR) T cells have shown remarkable success in treating hematologic cancers. However, this efficacy has yet to translate to treatment in solid tumors. Pancreatic ductal adenocarcinoma (PDA) is a fatal malignancy with poor prognosis and limited treatment options. We have dev...

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Detalles Bibliográficos
Autores principales: Yazdanifar, Mahboubeh, Zhou, Ru, Grover, Priyanka, Williams, Chandra, Bose, Mukulika, Moore, Laura J., Wu, Shu-ta, Maher, John, Dreau, Didier, Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770201/
https://www.ncbi.nlm.nih.gov/pubmed/31514488
http://dx.doi.org/10.3390/cells8091070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770201/
https://www.ncbi.nlm.nih.gov/pubmed/31514488
http://dx.doi.org/10.3390/cells8091070

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