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Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir

Viral persistency in latently infected CD4(+) T cells despite antiretroviral therapy (ART) represents a major drawback in the fight against HIV-1. Efforts to purge latent HIV-1 have been attempted using latency reversing agents (LRAs) that activate expression of the quiescent virus. However, initial...

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Detalles Bibliográficos
Autores principales: Desimio, Maria G., Covino, Daniela A., Doria, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770208/
https://www.ncbi.nlm.nih.gov/pubmed/31514330
http://dx.doi.org/10.3390/ijms20184490