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Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice

The aim of the present work was to address the role of BMP9 in different genetic backgrounds (C57BL/6, BALB/c, and 129/Ola) of mice deleted for Bmp9. We found that Bmp9 deletion led to premature mortality only in the 129/Ola strain. We have previously shown that Bmp9 deletion led to liver sinusoidal...

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Detalles Bibliográficos
Autores principales: Desroches-Castan, Agnès, Tillet, Emmanuelle, Ricard, Nicolas, Ouarné, Marie, Mallet, Christine, Feige, Jean-Jacques, Bailly, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770219/
https://www.ncbi.nlm.nih.gov/pubmed/31540222
http://dx.doi.org/10.3390/cells8091079