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Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation

A key role of the mitochondrial Translocator Protein 18 KDa (TSPO) in neuroinflammation has been recently proposed. However, little is known about TSPO-activated pathways underlying the modulation of reactive microglia. In the present work, the TSPO activation was explored in an in vitro human prima...

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Detalles Bibliográficos
Autores principales: Da Pozzo, Eleonora, Tremolanti, Chiara, Costa, Barbara, Giacomelli, Chiara, Milenkovic, Vladimir M., Bader, Stefanie, Wetzel, Christian H., Rupprecht, Rainer, Taliani, Sabrina, Da Settimo, Federico, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770267/
https://www.ncbi.nlm.nih.gov/pubmed/31510070
http://dx.doi.org/10.3390/ijms20184467