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The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients

Circulating cell-free DNAs (cfDNAs) are fragmented DNA molecules released into the blood by cells. Previous studies have suggested that mitochondria-originated cfDNA fragments (mt-cfDNAs) in cancer patients are more fragmented than those from healthy controls. However, it is still unknown where thes...

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Detalles Bibliográficos
Autores principales: An, Qin, Hu, Youjin, Li, Qingjiao, Chen, Xufeng, Huang, Jiaoti, Pellegrini, Matteo, Zhou, Xianghong Jasmine, Rettig, Matthew, Fan, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770274/
https://www.ncbi.nlm.nih.gov/pubmed/31598384
http://dx.doi.org/10.1093/pcmedi/pbz014