Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice

Tumor heterogeneity, especially intratumoral heterogeneity, is a primary reason for treatment failure. A single biopsy may not reflect the complete genomic architecture of the tumor needed to make therapeutic decisions. Circulating tumor DNA (ctDNA) is believed to overcome these limitations. We anal...

Descripción completa

Detalles Bibliográficos
Autores principales: Imperial, Robin, Nazer, Marjan, Ahmed, Zaheer, Kam, Audrey E., Pluard, Timothy J., Bahaj, Waled, Levy, Mia, Kuzel, Timothy M., Hayden, Dana M., Pappas, Sam G., Subramanian, Janakiraman, Masood, Ashiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770276/
https://www.ncbi.nlm.nih.gov/pubmed/31546879
http://dx.doi.org/10.3390/cancers11091399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770276/
https://www.ncbi.nlm.nih.gov/pubmed/31546879
http://dx.doi.org/10.3390/cancers11091399

Ejemplares similares