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Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells

Human induced pluripotent stem cells (iPSCs) can be differentiated in vitro into bona fide cardiomyocytes for disease modelling and personalized medicine. Mitochondrial morphology and metabolism change dramatically as iPSCs differentiate into mesodermal cardiac lineages. Inhibiting mitochondrial fis...

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Detalles Bibliográficos
Autores principales: Lees, Jarmon G., Kong, Anne M., Chen, Yi C., Sivakumaran, Priyadharshini, Hernández, Damián, Pébay, Alice, Harvey, Alexandra J., Gardner, David K., Lim, Shiang Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770295/
https://www.ncbi.nlm.nih.gov/pubmed/31641358
http://dx.doi.org/10.1155/2019/6380135