FGF23-Mediated Activation of Local RAAS Promotes Cardiac Hypertrophy and Fibrosis

Patients with chronic kidney disease (CKD) are prone to developing cardiac hypertrophy and fibrosis, which is associated with increased fibroblast growth factor 23 (FGF23) serum levels. Elevated circulating FGF23 was shown to induce left ventricular hypertrophy (LVH) via the calcineurin/NFAT pathway...

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Detalles Bibliográficos
Autores principales: Böckmann, Ineke, Lischka, Jonas, Richter, Beatrice, Deppe, Jennifer, Rahn, Anja, Fischer, Dagmar-Christiane, Heineke, Jörg, Haffner, Dieter, Leifheit-Nestler, Maren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770314/
https://www.ncbi.nlm.nih.gov/pubmed/31540546
http://dx.doi.org/10.3390/ijms20184634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770314/
https://www.ncbi.nlm.nih.gov/pubmed/31540546
http://dx.doi.org/10.3390/ijms20184634

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