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Transport-Mediated Oxaliplatin Resistance Associated with Endogenous Overexpression of MRP2 in Caco-2 and PANC-1 Cells

Our recent publications showed that multidrug resistance protein 2 (MRP2, encoded by the ABCC2 gene) conferred oxaliplatin resistance in human liver cancer HepG2 cells. However, the contribution of MRP2 to oxaliplatin resistance remains unclear in colorectal and pancreatic cancer lines. We investiga...

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Detalles Bibliográficos
Autores principales: Biswas, Riya, Bugde, Piyush, He, Ji, Merien, Fabrice, Lu, Jun, Liu, Dong-Xu, Myint, Khine, Liu, Johnson, McKeage, Mark, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770320/
https://www.ncbi.nlm.nih.gov/pubmed/31500349
http://dx.doi.org/10.3390/cancers11091330